CLARIOstar Plus Multi-Mode Plate Reader with LVF Monochromators, filters and UV/Vis spectrometer samples 100 measurements/second | 8000-89 displayed

Microplate Equipment,Spectrometers

Plate Reader; CLARIOstar Plus, Multimode, 1536 Well, UV/Vis Spectrometer, BMG LabTech

CLARIOstar Plus Multi-Mode Plate Reader with two LVF monochromators and a built-in UV/Vis spectrometer
Provides ultra-fast data sampling of 100 measurements per second
Dedicated laser for Alpha Technology, rapid full-plate autofocus and spectral scanning in ABS, FI and LUM
Upgradable unit integrates into automated systems
Enhanced Dynamic Range simplifies assay development ideal for kinetic assays

• Type: Plate Reader

• Plate Configuration: 1536 Well

• Reader Mode: Multimode

• Manufactured by: BMG LabTech

• Manufacturer SKU: CLARIOstar Plus

• Unit of Measure: EA

Manufacturer SKU: CLARIOstar Plus

Manufactured By: BMG Labtech

Warranty: One-Year Warranty for Parts and Labor

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Plate Reader; CLARIOstar Plus, Multimode, 1536 Well, UV/Vis Spectrometer, BMG LabTech

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Product Details

CLARIOstar Plus Multi-Mode Plate Reader with two LVF monochromators and a built-in UV/Vis spectrometer
Provides ultra-fast data sampling of 100 measurements per second
Dedicated laser for Alpha Technology, rapid full-plate autofocus and spectral scanning in ABS, FI and LUM
Upgradable unit integrates into automated systems
• Enhanced Dynamic Range simplifies assay development ideal for kinetic assays

Applications: Assay development, Real-time cell-based assays, Signaling, Protein-protein interaction, Fast kinetics, Cell/bacterial growth, Reporter gene analysis, Enzymatic reactions, Drug discovery, Metabolism, DNA/RNA quantification, Aggregation studies

Detection Modes: Fluorescence intensity (incl. FRET), Fluorescence polarization , AlphaScreen®/AlphaLISA®/AlphaPlexTM,, Luminescence (flash and glow) - incl. BRET, Time-resolved fluorescence, TR-FRET, UV/vis absorbance spectra

Measurement Modes: Top and bottom reading, Endpoint and kinetic, Sequential multi-excitation, Sequential multi-emission, Spectral scanning (fluorescence, luminescence, absorbance), Ratiometric measurements, Well scanning

Microplate Formats: 6- to 1536-well plates, user-definable. LVis Plate with 16 low volume microspots (2 μL) (sold separately)

CLARIOstar Plus Additional Features:

Microplate Carrier: Robot compatible

UV/Vis absorbance spectrometer: Full spectra or 8 distinct wavelengths in < 1 sec/well

Light Sources: High energy xenon flash lamp; Dedicated laser for AlphaScreen®/AlphaLISA®/AlphaPlexTM

Optical Filters: Excitation and emission slides for 4 filters each

Optical Path Guides: Top and bottom: free-air optical light path guided by motor-driven mirrors and dichroics

Z-Adjustment: Automatic focal height adjustment (0.1 mm resolution)

Shaking: Linear, orbital, and double-orbital with user-definable time and speed

Up to two integrated barcode readers

Incubation: +3 °C above ambient up to 45 °C or 65 °C

Conforms to SBS standards for microplates.

Low noise Photomultiplier Tube (PMT)

Fluorescence Excitation / Emission Spectral Scanning

Luminescence Emission Spectral Scanning

Detectors: Low-noise photomultiplier tube, Red-shifted photomultiplier tube, CCD spectrometer

Software: Multi-user Reader Control and MARS Data Analysis Software included; FDA 21 CFR Part 11 compliant

Software Selectable Bandwidths: 8 - 100 nm

Prevents condensation build-up on lid or sealer with upper heating plate of incubation chamber operating at 0.5 °C more than the lower plate

Wavelength Selection

Dual Linear Variable Filter (LVF) Monochromators™

Linear Variable Dichroic Mirror

Separates ex & em LVF Monochromators

Optical filters: excitation and emission slides hold up to 4 filters each

LVF Monochromators + optical fi liters: use one for excitation and the other for emission

UV/vis absorbance spectrometer: full spectra or 8 discrete wavelengths in < 1 sec/well

Optical filters: Ex and em slides hold 4 filters each, LVF Monochromators + optical filters

Spectral Range

Filters: FI, FP, TRF: 240 - 740 nm or 240 - 900 nm (red-shifted PMT); LUM: 240 - 740 nm

LVF Monochromators: FI: 320 - 740 nm or 320 - 840 nm (red-shifted PMT); LUM: 320 - 740 nm

Linear Variable Dichroic: 340 - 740 nm or 340 - 760 nm (red-shifted PMT)

Spectrometer: ABS 220 - 1000 nm; wavelength precision: ≤ 0.5 nm

Accuracy: < 1% at 2 OD

Precision: < 0.5% at 1 OD and < 0.8% at 2 OD

Linearity: ≤ 0.8% at 2.0 OD

Read Times

Flying mode (1 flash): 8 s (96), 15 s (384), 28 s (1536)

10 flashes: 19 s (96), 57 s (384), 3 min 4 s (1536)

Reagent Injection

Up to 2 built-in reagent injectors

Individual injection volumes for each well: 3 to 500 µL (optionally up to 2 mL)

Variable injection speed up to 420 µL / s

Reagent back flushing

Optional Accessories

LVis Plate (or 2 µL samples), THERMOstar Microplate incubator and shaker

Quality Control Internal Standards (optional): four NIST traceable optical density filters (approximate values of 0.1, 0.3, 0.6 and 1.0 OD); one holmium oxide filter for wavelength accuracy

Stacker Magazines for up to 50 plates – continuous loading feature

Optical Filters Excitation and emission filters

Upgrades: Contact a product specialist for details

LOD = 3 x SD (20 blanks) / slope (6 pt std curve)

AlphaScreen® P-Tyr-100 assay kit, PerkinElmer, #6760620C

Microplates: white for LUM, AlphaScreen®, TRF; black for FI, FP; clear for ABS

96 = 96-well microplates

384sv = 384-well small volume microplates

384g = 384-well glass bottom microplates

1536 = 1536-well microplates

• Type: Plate Reader

• Plate Configuration: 1536 Well

• Reader Mode: Multimode

• Manufactured by: BMG LabTech

• Manufacturer SKU: CLARIOstar Plus

• Unit of Measure: EA

• Weight, Product: 70.5 lb

• Dimensions, Product: 17.7" W x 20.07" D x 15.7" H

Manuals & Resources

Microplate Equipment

Features and Benefits

Patented LVF Monochromator

Filter-like performance provides highest sensitivity and flexibility by separating light into distinct wavelengths and into continuous adjustable bandwidths

Built-in UV/Vis Spectrometer

BMG LabTech Plate Readers are equipped with a UV/Vis Spectrometer for absorbance measurements that captures a full spectra from 220-1000 nm in less than one second per well

Simplifies Assay Setup

Enhanced Dynamic Range (EDR) Technology simplifies detection optimization by automatically measuring samples with ideal settings

LVis Low-Volume Microplate

BMG LabTech UV/Vis Absorbance spectrometer-based microplate readers are compatible with LVis Low-volume Microplate with cuvette slots for 2ul Samples (Sold Separately)